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Bioinformatics: From Genomes to Drugs, 2 Volume Set

ISBN-10:3-527-29988-2
ISBN-13:978-3-527-29988-1

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General descriptionBioinformatics promises to revolutionize the process of drug discovery and development. This book provides an application-oriented overview of this technology. In addition, the state-of-the-art in bioinformatics is evaluated from a global view by introducing real application scenarios such as genome projects that require the use of a whole set of bioinformatics tools. The knowledge on bioinformatics presented enables readers to go beyond a mere push-button approach to using bioinformatics software and interpreting the data generated, but also to assess the potential and limitations of today's bioinformatics software and future challenges.

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publication infoT. Lengauer, et al., Wiley-VCH, 2002, 688 pp., hard cover

Table Of Contents

Table of ContentsVOLUME I.
From Genomes to Drugs with Bioinformatics - An Overview.
Sequence Analysis.
Structure, Properties and Computer Identification of Eukaryotic Genes.
Analyzing Regulatory Regions in Genomes.
Homology Modeling in Biology and Medicine.
Protein Structure Prediction.
Protein-Ligand Docking in Drug Design.
Modelling Protein-Protein and Protein-DNA Docking.
Appendix: Algorithmic Methods in Bioinformatics.
VOLUME II.
Integrating and Accessing Molecular Biology Resources.
Bioinformatics Support of Genome Sequencing Projects.
Analysis of Sequence Variations.
Proteome Analysis.
Target Finding in Genomes and Proteomes.
Screening of Drug Databases.
Future Trends.